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Drug update

Biological therapies for rheumatoid arthritis: TNF inhibitors

John HY Moi, Russell RC Buchanan

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Abstract

The advent of TNF inhibitors represents a significant advance in treatment options for patients with rheumatoid arthritis who are refractory to traditional DMARD therapy.

Article Extract

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder of unknown aetiology. It is the most common form of inflammatory arthritis and affects about 0.5 to 1% of the adult population worldwide. The peak incidence of disease onset occurs in people aged between 20 and 40 years, with women representing three-quarters of all those diagnosed with the condition.

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