Dermatology clinic

Itchy blisters on exposed skin

Steven Kossard
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A woman presents with pruritic blisters, at various stages of evolution, over her limbs. What are they?

Article Extract

Case history

Over a two-week period, a 23-year-old woman developed blisters over her limbs. The blisters commenced as erythematous papules. There were asynchronous lesions present at different stages of evolution. Skin biopsy showed a large subepidermal blister containing strands of fibrin. The underlying dermis had superficial and deep perivascular and interstitial lymphocytes and eosinophils.