Eyelid lesions can range from benign lumps to malignant and potentially blinding and deadly disease, if missed. Initial presentations commonly take place in the primary healthcare setting, therefore early recognition of suspicious eyelid lesions is crucial.
An understanding of eyelid margin structures is necessary for diagnosis of an eyelid lesion. Structures include the skin, subcutaneous tissue, orbicularis oculi muscle, tarsus, retroseptal fat pads and the conjunctiva. Adnexal structures include eyelashes, glands of Zeis and Moll, glands of Wolfring and Krause, meibomian glands and the associated vascular and lymphatic supply (Figure 1).