Widespread tense blisters
A 52-year-old woman presents with widespread pruritic, tense blisters on her trunk and limbs. There are no mucous membrane lesions.
Progressive facial slate-grey pigmentation
A 68-year-old man presented with asymptomatic progressive pigmentation, confined to the sun-exposed sites of his face and hands. Details of his drug history plus a skin biopsy with UV light microscopy revealed the diagnosis.
Itchy coin-shaped lesions
A 43-year-old man presented with pruritic, round, crusted lesions on his limbs. The size of the lesions varied, and there was a vesicular border.
Intermittently itchy reddish-brown spots
A 32-year-old man presents with persistent and numerous reddish-brown spots on his limbs and trunk. The lesions are stable, but occasionally there is an urticarial reaction when they are rubbed. A skin biopsy confirmed the diagnosis.
A pearly nodule on the back
A 38-year-old man presents with a smooth, shiny and well demarcated pearly nodule on his upper back. The nodule is asymptomatic and of unknown duration.
Recurrent dusky skin lesions
A 35-year-old woman presents with erythematous lesions on her upper limbs and trunk shortly after taking antibiotics for a urinary tract infection.
Progressive pigmented purpura
A 42-year-old woman presents with progressive yellow–brown pigmentation associated with nonpalpable purpura over her shins.
An acute pustulovesicular eruption
A middle-aged woman presents with a recent history of tender annular and bow-shaped pustular lesions on her face, neck, and upper limbs.
Scarring alopecia with tufted folliculitis
A 34-year-old woman presents with an 18-month history of progressive hair loss, associated with tenderness, on her scalp. Tufted follicles and scarring alopecia were the key to diagnosis.
Skin necrosis with vascular calcification
A 59-year-old woman with chronic renal failure presents with a recent history of multiple progressive, painful ulcers over the lower limbs.