Peer Reviewed
Feature Article Drug and alcohol medicine
Recent developments in smoking cessation
Abstract
New research into nicotine replacement therapy (NRT) has delivered creative ways to enhance the use and effectiveness of existing products, such as pre-quit treatment with nicotine patches, combination NRT and the use of nicotine products in unmotivated smokers. The new drug varenicline is another potent tool for helping smokers quit.
Key Points
- Pharmacotherapy should be offered to all motivated smokers who are nicotine dependent.
- Nicotine patches should be started two weeks before quitting in motivated smokers.
- Nicotine gum or a nicotine inhaler should be used to help unmotivated smokers quit.
- The most effective therapies are combination nicotine replacement therapy, varenicline and pre-quit nicotine patches.
- Nicotine replacement therapy should be continued after a lapse to prevent progression to a full relapse.
- The new drug varenicline is an effective and well-tolerated first-line smoking cessation therapy.
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