November 2015 Peer Reviewed Feature Articles Adult depression: a step-by-step guide to treatment CPD OPEN ACCESS Josephine Anderson, Verònica Gálvez, Colleen K Loo, Philip B Mitchell Investigating primary and secondary amenorrhoea CPD Michelle Wellman The cardiac complications of obesity CPD Elizabeth Paratz, Sonny Palmer, Justin Mariani Investigation of patients presenting with headache CPD Miriam Wronski, Alessandro S Zagami Advertisement Peer Reviewed Regular Series Emergency medicine Acute ankle and knee injuries: to x-ray or not? Gordian Fulde Therapeutics clinic Changes to PBS criteria for testosterone prescribing Rob McLachlan Medicolegal matters ‘I’ve never had such a bad headache’: a missed diagnosis Nicole Kroesche, Walid Jammal Gastroenterology clinic Irritable bowel syndrome: what to do when dietary manipulation fails James Haridy, Geoff Hebbard Dermatology clinic A macular, speckled and melanocytic lesion Andrew Lee, Gayle Fischer Advertisement In Brief Clinical news with comment from local experts Occupational bladder cancer Asthma in children Pre-pregnancy exercise benefits Treating MI in young women CLINICAL NEWS Bladder cancer: some workers remain at high risk Children with asthma exposed to cigarette smoke: doubled risk of hospitalisation Regular pre-pregnancy exercise reduces pelvic girdle pain during pregnancy Fewer young women with MI receiving drug therapy Macular degeneration helped by carotenoids Self-harm risk after bariatric surgery Corrections NEWSBITES Aboriginal and Torres Strait Islander health worker resource on breast cancer Premature deaths in Australia Advertisement