October 2009 Peer Reviewed Feature Articles Fibromyalgia: mechanisms and management Geoffrey O Littlejohn, Emma Guymer Is it possible to distinguish bipolar depression from unipolar depression? Philip B Mitchell Clinical approach to the patient with peripheral oedema Craig Juergens, Patrick Diu Treatment options for men with osteoporosis Terry Diamond, Peter R Ebeling Advertisement Peer Reviewed Regular Series Ophthalmology clinic Corneal transplantation – indications and current techniques Katie Chen, Graham A Lee Clinical case review A young girl in need of contraception: the legal position of the GP Christine Read Sexual health Postexposure prophylaxis for HIV following sexual exposure David J Templeton Drug update Sitagliptin and metformin combination therapy for type 2 diabetes Timothy ME Davis Advertisement Advertisement