Perspectives

The importance of iron deficiency in heart failure

Sean M. Conte, Hannah Kempton, Callum Cherrett, Christopher Hayward
Iron deficiency, even in the absence of anaemia, in patients with heart failure is common, multifactorial and associated with worse outcomes.
Lipid disorders

Lipid management – what counts, what is new?

Leon A. Simons

Lipid-modifying therapy reduces cardiovascular disease (CVD) risk in many patients, especially in those with pre-existing CVD. Lipid- lowering therapies include statins, ezetimibe and PCSK9 inhibitors, with promising new therapies currently in development.

Case review

Untangling chronic breathlessness in primary care

Anthony P. Sunjaya, Leanne M. Poulos, Helen K. Reddel, Christine R. Jenkins
A 37-year-old teacher presents with breathlessness on exertion that has been affecting her ability to exercise over the past three years. How would you investigate and manage her?
Perspectives

What is nociplastic pain?

Milton Cohen
The term ‘nociplastic pain’ has been introduced as the third mechanistic descriptor for the somatic component of pain. This article defines this new term and explains the significance of its introduction.