Gastroenterology clinic

Elevated serum ferritin: identifying iron overload

Fei Wen Chen, Amany Zekry
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It is important to determine whether elevated ferritin levels are associated with iron overload conditions, such as hereditary haemochromatosis, or other causes, such as liver or inflammation-related conditions.

Article Extract

  • Ferritin, an iron storage protein, is critical to iron haemostasis. Its serum concentration closely reflects the body iron stores in the absence of inflammation.
  • Alterations in ferritin level are seen commonly in clinical practice, often reflecting perturbations in iron homeostasis or metabolism.

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