Feature Article

Personalising prostate cancer care. Part 2. Current treatment options

Amila Siriwardana, James Thompson, Phillip D Stricker



Treatment for men with prostate cancer can now be tailored according to patient, tumour, imaging and genetic factors. Current options include active surveillance, whole-gland surgery (including open, laparoscopic and robot-assisted techniques), radiotherapy (with improved targeting allowing higher doses), emerging focal therapies, chemotherapy and hormone therapy.

Key Points

  • Personalised tailored therapy for men with prostate cancer is now available.
  • For men with low-risk prostate cancer, active surveillance is safe and minimises the quality-of-life burden that can accompany whole-gland therapy.
  • Surgery or radiotherapy can be used for definitive treatment of localised prostate cancer.
  • Focal therapy is emerging as a middle-ground option for selected patient groups.
  • Men with high-risk or locally advanced prostate cancer usually require combination therapy.
  • For men with advanced metastatic prostate cancer, hormone therapy remains the ‘gold standard’ treatment.

    Picture credit: © Alex and David Baker