Peer Reviewed
Feature Article Women’s health

Late onset and postadolescent acne in women

Keng Chen, Jo-Ann See
Abstract
Assessment of patients with late onset or postadolescent acne should include identifying the presence of hyperandrogenism and possible underlying causes. Management options include topical keratolytics and antibiotics, systemic antibiotics, isotretinoin and hormonal agents.
Key Points
  • Late onset acne is acne that develops at or after the age of 20 years, whereas postadolescent acne is acne continuing past the teenage years.
  • Females may have normal or raised serum androgen levels.
  • Polycystic ovary syndrome is often an underlying cause in women with late onset or persistent acne.
  • Assessment should include a menstrual history and examination for clinical signs of hyperandrogenism, such as hirsutism.
  • Hormonal therapy is a very effective adjunct in the management of these patients, including those with normal serum androgen profiles.
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