Peer Reviewed
Feature Article Gastroenterology

Investigation and management of noncardiac chest pain

Geoff Hebbard, Claudia Gruebel
Abstract

Noncardiac chest pain is common and diagnosis can be difficult; however, in most cases patients can be reassured that the natural history is benign. Gastro-oesophageal reflux disease is the most common underlying cause; resolution of symptoms after treatment with a proton pump inhibitor may obviate the need for further investigations.

Key Points
    • Noncardiac chest pain (NCCP) is common and diagnosis can be difficult; however, in most cases the natural history is benign.
    • The most common underlying cause of NCCP is gastro-oesophageal reflux disease. Resolution of symptoms following treatment with a proton pump inhibitor (PPI) may obviate the need for further investigations.
    • If treatment with a PPI is not effective, other causes should be sought and treated.
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