Although nausea is a symptom of primary gastrointestinal disease, there are many other causes. Here, these authors outline their approach to nausea.
- Nausea is a nonspecific symptom of extremely diverse aetiology.
- The chemoreceptor trigger zone in the medulla is sensitive to drugs, toxins and neurotransmitters, and the nucleus tractus solitarius, also in the medulla, is sensitive to visceral afferents. Projections from the medulla to the limbic, hypothalamic and cortical regions of the CNS allow for perception of nausea.