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Gastroenterology clinic

How to manage drugs and PEGs

Michelle Jenkins, Anne Duggan

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Abstract

Patients who are being fed via gastrostomy tubes often need medicines to be administered by the same route.

Article Extract

Remember
  • Use alternatives to solid oral formulations of medicines for patients with a percutaneous endoscopic gastrostomy (PEG) whenever possible. Parenteral alternatives are generally only a short term solution. Liquid oral medications should be mixed with a small volume of water prior to administration via a PEG if they are viscous. Topical alternatives include transdermal patches, enemas and suppositories.
  • Consider the effect of food. Administer drugs whose gastrointestinal absorption is impaired in the presence of food either half an hour before or two hours after a feed. Decreased absorption of such drugs, and possibly subtherapeutic responses, may occur in patients undergoing a continuous feeding regimen.

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