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Friday 19 April 2024

Peer Reviewed

Gastroenterology clinic

Managing fluid retention in cirrhosis

Uthayanan Chelvaratnam, Katherine Stuart

Recent articles on:
Cirrhosis

Managing the rising burden of chronic liver disease: nonalcoholic fatty liver disease and alcoholic liver disease

Managing fluid retention in cirrhosis

Noninvasive tests for assessing liver fibrosis

Cirrhosis: a management guide

Investigating the patient with ascites

Recent articles on:
Liver diseases

Intestinal failure – improving long-term survival

Haemochromatosis – a clinician’s guide

Nonviral hepatitis: common causes and their management

Nonalcoholic fatty liver disease

Abnormal liver function test results in pregnancy – causes and management

Abstract

Fluid retention in cirrhosis, which most often manifests as ascites, is associated with a poor prognosis. All patients who develop ascites should be referred for specialist hepatology input.

Key Points

Remember

Ascites is the most common complication of cirrhosis (Figure 1), affecting 60% of patients over a 10-year period.
The presence of ascites is a sign of liver failure and is associated with a five-year mortality of 30%.2 Hepatic encephalopathy and variceal haemorrhage are other signs of liver failure.
Signs of fluid retention that are less often observed in patients with cirrhosis include peripheral oedema and hepatic hydrothorax (5 to 10%) and are almost always observed in association with ascites. Hepatic hydrothorax is usually right-sided, but it can be left-sided or bilateral.