Premature ovarian insufficiency, which is defined as loss of ovarian activity before the age of 40 years, has negative health impacts. Prompt diagnosis, evaluation of cause and sequelae, psychological support and institution of hormone replacement therapy are essential components of management.
Premature ovarian insufficiency (POI), also known as premature menopause or premature ovarian failure, is defined as the loss of ovarian activity before the age of 40 years.1 It may occur spontaneously or secondary to medical treatments. Management should incorporate consideration of symptoms experienced, psychological health and desire for fertility, as well as the long-term sequelae related to bone and cardiovascular health. Hormone replacement therapy is recommended until the age of natural menopause.