Peer Reviewed
Drug update
Reuptake inhibitors for depression
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Recent articles on:
Depression
Depression
Recent articles on:
Antidepressants
Antidepressants
Abstract
The newer neurotransmitter reuptake inhibitors, because of their greater selectivity, have significant advantages in safety and side effects compared with the original reuptake inhibitors, the tricyclics.
Key Points
The management of depression advanced greatly with the development of antidepressant agents based on neurotransmitter reuptake inhibition and, more recently, the development of reuptake inhibitors selective for specific neurotransmitters. These newer antidepressants have fewer side effects and less toxicity than the older agents. The pharmacology of the reuptake inhibitors, and particularly the newer drugs, is discussed in this article.
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