Therapeutics clinic

Adrenaline injectors – update on prescribing

Therapeutics clinic

Adrenaline injectors – update on prescribing

Katie Frith, JILL SMITH, CONSTANCE H. KATELARIS

Figures

© YULIA SHEVTSOVA/ STOCK.ADOBE.COM model used for illustrative purposes only
© YULIA SHEVTSOVA/ STOCK.ADOBE.COM model used for illustrative purposes only

Abstract

Adrenaline (epinephrine) is the first-line treatment for anaphylaxis, and two types of adrenaline injector are available for use in Australia. Prescribers need to be aware of the different instructions for their use and recent changes to adrenaline dose recommendations.

Article Extract

Anaphylaxis is a severe, potentially life-threatening allergic reaction, and intramuscular (IM) adrenaline (epinephrine) is the treatment of choice.1-4 Adrenaline injectors (AI) have been available for more than 40 years and allow rapid administration of IM adrenaline by the patient or a lay person.5-7 In Australia, the EpiPen AI has been available on the PBS since 2003. From 2021, a second type of AI device that can deliver a higher dose is also available on the PBS, Anapen. Here, we discuss the role of AIs in treating anaphylaxis, how to prescribe them, including dose and patient education, and compare EpiPen and Anapen.