Peer Reviewed
Feature Article Cardiovascular medicine

Investigation and management of xanthoma

Leon A Simons
Abstract
Xanthoma around the eyelids (xanthelasma) is a common presentation; other xanthomas are quite rare. The presence of xanthoma may indicate an underlying blood lipid disorder, and patients should have a full liid profile and biochemical screen performed.
Key Points
  • Xanthoma around the eyelids (xanthelasma) is a common presentation in general practice; tendon xanthoma and cutaneous xanthoma are quite rare.
  • Many patients with xanthoma have an underlying blood lipid disorder.
  • All patients with xanthoma should have a fasting lipid profile and a standard haematology and biochemistry work up.
  • Ongoing management is related to any lipid disorder diagnosed.
  • Specialist referral may be desirable for severe lipid disorders.
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