December 2024

Peer Reviewed Feature Articles
Renal medicine

Diabetic kidney disease: the four pillars of therapy

Catherine Zheng, Amanda Mather, Sarah Roxburgh, Brendon L. Neuen, Jeffrey T. Ha

The management of diabetic kidney disease secondary to type 2 diabetes now centres on four ‘pillars’ of treatment, in addition to lifestyle modification. Early implementation of these therapies can have a significant impact on long-term outcomes for patients with this condition.

CPD
Complete 1.5 CPD hours
Free Access
Free access
Neurology

What to do when SSRI and SNRI antidepressants don’t work – a guide for GPs

Philip B. Mitchell

Only a third of patients with depression achieve remission with first-line selective serotonin reuptake inhibitors (SSRIs). What should be done when patients with depression either fail to respond to, or do not tolerate, SSRIs and serotonin-noradrenaline reuptake inhibitors?

CPD
Complete 1.5 CPD hours
Obesity

Obesity: a therapeutic target in people with cardiovascular disease

Jennifer Sun, John J. Atherton

Obesity management is an important priority to reduce the burden of incident and recurrent cardiovascular events. Lifestyle management remains a cornerstone of management; however, the pharmacological treatment landscape is rapidly evolving with recent trials demonstrating the benefit of glucagon-like peptide-1 receptor agonists in inducing weight loss and reducing cardiovascular events.

Peer Reviewed Regular Series
Dermatology clinic

Erythema nodosum: presentation and treatment

Xin Lin Wong, Stephen Shumack

The presence of erythema nodosum, the most prevalent type of panniculitis, warrants consideration of a range of potential triggers and investigation.

Clinical case review

RSV infection in an infant

Emily Le Fevre, Dominic Fitzgerald

How should this 5-month-old boy who presents in general practice with two days of fever, cough and runny nose be assessed and what are the next steps in management?

Physician-authored summaries and commentary on the most important medical research, provided by the NEJM Group, a division of the Massachusetts Medical Society.

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